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What phrase represents accurate information about the pharmacokinetics of lithium?


A) Wide therapeutic index
B) Excreted by the kidneys
C) Poorly absorbed in the gastrointestinal (GI) tract
D) Provides immediate relief of symptoms

E) A) and C)
F) C) and D)

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The spouse of a patient diagnosed with bipolar disorder tells the nurse, "Every time my partner recovers from a manic episode, depression follows soon.It's very discouraging." The nurse's reply should include what information?


A) As the partner ages, rapid cycling will decrease.
B) Combining lithium with haloperidol (Haldol) might prevent rapid cycling.
C) Depression associated with bipolar disorder is usually time-limited, so treatment is not indicated.
D) Recent addition of olanzapine to this patient's drug regime can be helpful as a mood stabilizer.

E) None of the above
F) A) and B)

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A patient diagnosed with bipolar disorder asks the nurse, "Why can't I take my lithium just once a day at bedtime? It's hard to remember to take it three times." The nurse's reply should be based on what information?


A) The half-life of lithium is short.
B) Renal excretion is greater at night.
C) GI absorption is diminished at night.
D) The toxicity potential increases with once-a-day dosing.

E) All of the above
F) B) and C)

Correct Answer

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