Question 1

What fate often awaits granulocytes that have entered the marginating compartment?

Accepted Answer

A)   Undergo mitosis
B)   Crossing the wall of a venule to enter connective tissue
C)   Cannot reenter the circulation
D)   Differentiate into functional macrophages
E)   Begin to release plateletsF) D) and E)
G) A) and D)

Question 2

A 54-year-old man presents with recurrent breathlessness and chronic fatigue. After routine tests followed by a bone marrow biopsy he is diagnosed with lymphocytic leukemia. Chemotherapy is administered to remove the cancerous cells, which also destroys the precursor cells of erythrocytes. To reestablish the erythrocytic lineage, which of the following cells should be transplanted?

Accepted Answer

A)   Reticulocytes
B)   Orthochromatophilic erythroblasts
C)   Megakaryoblasts
D)   Basophilic erythroblasts
E)   MetamyelocytesF) A) and D)
G) A) and C)

Question 3

Which cytoplasmic components are the main constituents of the dark precipitate that forms in reticulocytes upon staining with the dye cresyl blue?

Accepted Answer

A)   Golgi complexes
B)   Hemoglobin
C)   Nucleoli
D)   Nuclear fragments
E)   PolyribosomesF) None of the above
G) C) and D)

Question 4

What is the earliest stage at which specific granulocyte types can be distinguished from one another?

Accepted Answer

A)   Myelocyte
B)   Band form
C)   Reticulocyte
D)   Metamyelocyte
E)   PromyelocyteF) B) and E)
G) B) and C) A

Question 5

Shortly after her birth a baby is diagnosed with a mutation in the erythropoietin receptor gene which leads to familial erythrocytosis (familial polycythemia) . During the seventh to ninth months of fetal development, the primary effect on her red blood cell production was in which of the following?

Accepted Answer

A)   Liver
B)   Yolk sac
C)   Spleen
D)   Thymus
E)   Bone marrowF) B) and E)
G) B) and D)

Question 6

Which process occurs during granulopoiesis but not during erythropoiesis?

Accepted Answer

A)   Cells lose their capacity for mitosis
B)   Euchromatin content increases
C)   Nucleus becomes increasingly lobulated
D)   Overall cell diameter decreases
E)   Overall nuclear diameter decreasesF) B) and E)
G) D) and E) C

Question 7

Which of the following can be used to describe megakaryocytes?

Accepted Answer

A)   Multinucleated
B)   Formed by fusion of haploid cells
C)   Precursors to bone marrow macrophages
D)   A minor but normal formed element found in the circulation
E)   Possess dynamic cell projections from which one type of formed element is releasedF) A) and D)
G) A) and C)

Question 8

In which of the following cells involved in erythropoiesis does hemoglobin synthesis begin?

Accepted Answer

A)   Orthochromatic erythroblast
B)   Polychromatophilic erythroblast
C)   Reticulocyte
D)   Basophilic erythroblast
E)   ProerythroblastF) D) and E)
G) B) and C)

Question 9

A smear of blood from a 70-year-old leukemia patient reveals a larger than normal population of cells that have large, round nuclei with one or two nucleoli. The cytoplasm of these cells shows azurophilic granules. Which of the following forms of leukemia would you suspect?

Accepted Answer

A)   Promyelocytic leukemia
B)   Basophilic leukemia
C)   Lymphoblastic leukemia
D)   Stem cell leukemia
E)   Eosinophilic leukemiaF) A) and E)
G) All of the above

Question 10

Which cell type is capable of further mitosis after leaving the hemopoietic organ in which it is formed?

Accepted Answer

A)   Basophil
B)   Eosinophil
C)   Reticulocyte
D)   Lymphocyte
E)   NeutrophilF) D) and E)
G) All of the above D

Exam 13: Hemopoiesis

What fate often awaits granulocytes that have entered the marginating compartment?

Correct Answer
verified

Correct Answer
verified

Which cytoplasmic components are the main constituents of the dark precipitate that forms in reticulocytes upon staining with the dye cresyl blue?

Correct Answer
verified

What is the earliest stage at which specific granulocyte types can be distinguished from one another?

Correct Answer
verified
A

Shortly after her birth a baby is diagnosed with a mutation in the erythropoietin receptor gene which leads to familial erythrocytosis (familial polycythemia) . During the seventh to ninth months of fetal development, the primary effect on her red blood cell production was in which of the following?

Correct Answer
verified

Which process occurs during granulopoiesis but not during erythropoiesis?

Correct Answer
verified
C

Which of the following can be used to describe megakaryocytes?

Correct Answer
verified

In which of the following cells involved in erythropoiesis does hemoglobin synthesis begin?

Correct Answer
verified

A smear of blood from a 70-year-old leukemia patient reveals a larger than normal population of cells that have large, round nuclei with one or two nucleoli. The cytoplasm of these cells shows azurophilic granules. Which of the following forms of leukemia would you suspect?

Correct Answer
verified

Which cell type is capable of further mitosis after leaving the hemopoietic organ in which it is formed?

Correct Answer
verified
D

Exam 13: Hemopoiesis

What fate often awaits granulocytes that have entered the marginating compartment?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Which cytoplasmic components are the main constituents of the dark precipitate that forms in reticulocytes upon staining with the dye cresyl blue?

Correct AnswerverifiedShow Answer

What is the earliest stage at which specific granulocyte types can be distinguished from one another?

Correct AnswerverifiedA

Correct AnswerverifiedShow Answer

Which process occurs during granulopoiesis but not during erythropoiesis?

Correct AnswerverifiedC

Which of the following can be used to describe megakaryocytes?

Correct AnswerverifiedShow Answer

In which of the following cells involved in erythropoiesis does hemoglobin synthesis begin?

Correct AnswerverifiedShow Answer

A smear of blood from a 70-year-old leukemia patient reveals a larger than normal population of cells that have large, round nuclei with one or two nucleoli. The cytoplasm of these cells shows azurophilic granules. Which of the following forms of leukemia would you suspect?

Correct AnswerverifiedShow Answer

Which cell type is capable of further mitosis after leaving the hemopoietic organ in which it is formed?

Correct AnswerverifiedD

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
A

Correct Answer
verified

Correct Answer
verified
C

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
D