Filters
Question type

Study Flashcards

The cultured human cell line HeLa expresses the E6 and E7 proteins of human papillomavirus.What would happen to these cells if the expression of these proteins was shut off?


A) They would continue to grow at their usual pace
B) They would continue to grow, just more slowly.
C) They enter the Gā‚€ phase of the cell cycle.
D) They go into apoptosis and die.
E) They become even more tumorigenic.

F) A) and D)
G) D) and E)

Correct Answer

verifed

verified

The Pap test, named after George Papanicolaou, screens for the presence of cancer cells in the cervix.

A) True
B) False

Correct Answer

verifed

verified

Which of the following cellular events causes the papillomavirus to enter "vegetative replication"?


A) Induction of the apoptosis pathway.
B) Entry into the S phase of the cell cycle.
C) Terminal differentiation of keratinocytes.
D) Cell division of the host cell.
E) Transformation into a cancer cell.

F) B) and E)
G) C) and D)

Correct Answer

verifed

verified

Explain the roles that plasmid replication and vegetative replication play in the life cycle of papillomaviruses as they infect stratified epithelium.

Correct Answer

verifed

verified

Papillomaviruses initially infect the ba...

View Answer

Papillomaviruses replicate in differentiated keratinocytes, which are not actively dividing.How does the virus handle this situation?


A) They encode their own DNA replication enzymes.
B) Plasmid replication in the basal cells produces enough copies of the viral genome.
C) The viral E2 protein directly activates transcription of DNA replication genes.
D) The viral E6 protein binds to the p53 protein, causing it to be degraded.
E) The viral E7 protein binds to the pRb protein, forcing the cell into S phase.

F) A) and D)
G) A) and C)

Correct Answer

verifed

verified

Showing 21 - 25 of 25

Related Exams

Show Answer